Gary Sinise’s son, McCanna “Mac” Sinise has died from a rare form of cancer at the age of 33.

The Gary Sinise Foundation shared the news on Instagram, with the caption, “In Honor & Memory of McCanna ‘Mac’ Sinise 1990-2024.”

In a statement, the foundation revealed that Mac was diagnosed with a very rare cancer called Chordoma on August 8, 2014. Chordoma is a type of cancer that originates in the spine and affects only about 300 people in the U.S. per year.

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Gary and his son, Mac Sinise. Gary’s son died after a battle with a rare form of cancer. (Gary Sinise Foundation)